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目的:采用Meta分析评价点刺四缝穴治疗小儿疳积的临床疗效。方法:以“疳积”“疳证”“积滞”和“四缝”为关键词,检索Cochrane Library、Pub Med、CNKI、Wanfang、VIP数据库从建库至2015年12月的相关文献,运用Review Manager5.3软件进行Meta分析。结果:最终纳入14篇临床随机对照试验,共1978例患者,文献研究质量均较低。Meta分析结果显示,使用不同疗法治疗小儿疳积时,点刺四缝穴疗效优于非点刺四缝穴,差异有统计学意义[OR=4.00,95%CI(3.05,5.25)],漏斗图不对称提示有发表偏倚。结论:点刺四缝穴治疗小儿疳积在总体疗效方面显示出一定优势,但由于文献质量较低并且可能存在发表偏倚,仍然需要更多的高质量研究增加证据强度。
OBJECTIVE: To evaluate the clinical curative effect of treating acupoints in children by means of Meta-analysis. METHODS: The Cochrane Library, Pub Med, CNKI, Wanfang and VIP databases were searched from the database to 2015 with the keyword “” “” " December of the relevant literature, the use of Review Manager5.3 software for meta-analysis. RESULTS: A total of 14 RCTs were included in the study, and a total of 1978 patients were included. The quality of the literature was low. Meta-analysis showed that the curative effect of puncturing four-slit points was better than that of non-puncturing four-slit points when using different therapies to treat infantile malnutrition [OR = 4.00,95% CI (3.05,5.25)], Figure asymmetry suggests publication bias. CONCLUSIONS: The treatment of infantile malnutrition at the point of Siqiu points shows some advantages in overall efficacy. However, due to the low quality of the literature and the possible publication bias, more high-quality studies are still needed to increase the strength of evidence.