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目的探讨铁粒幼细胞性贫血(SA)与难治性贫血(MDS-RARS)的临床及细胞形态学特点的鉴别。方法对25例SA和45例MDS-RARS的初诊资料进行回顾性比较研究。结果SA和MDS-RARS临床表现相似,很难鉴别,两组外周血粒系、红系、巨核三系均减少。骨髓铁染色中都有环铁幼细胞,红系均有病态造血。RARS有一定程度的三系病态造血。结论细胞形态学对鉴别SA和MDS-RARS有重要价值,必要时可行其他辅助实验检查,以提高二者之间的鉴别诊断水平。
Objective To investigate the clinical and cytomorphological features of subgroup Amyloidosis (AI) and refractory anemia (MDS-RARS). Methods The data of 25 cases of SA and 45 cases of MDS-RARS were compared retrospectively. Results The clinical manifestations of SA and MDS-RARS were similar and it was difficult to identify the two groups of peripheral blood, erythroid and megakaryocyte lines were reduced. There are iron ring cells in bone marrow iron staining, erythroid all have pathological hematopoiesis. RARS has a certain degree of morbid hematopoiesis. Conclusion Cell morphology has important value in differentiating SA from MDS-RARS. If necessary, other auxiliary tests may be performed to improve the differential diagnosis between SA and MDS-RARS.