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目的:评价经尿道膀胱肿瘤电切术(transurethral resection of bladder tumor,TURBT)在治疗高龄膀胱癌合并反复性出血中的疗效及安全性。方法:2003年5月~2013年5月共收治高龄膀胱癌合并反复性出血患者62例,行TURBT治疗。结果:62例患者手术均顺利完成,无术中死亡,无术中输血;术后常规用丝裂霉素40 mg+0.9%生理盐水40 ml进行膀胱灌注化疗。术后采用电话随访,随访时间为6~60个月,平均32个月;均能达到良好止血效果,患者生活质量明显改善,5年生存率为79.0%。结论:TURBT处理高龄膀胱癌合并反复性出血止血效果达100%,安全系数高,术后配合丝裂霉素化疗,达到治疗及改善生存质量的目的。
Objective: To evaluate the efficacy and safety of transurethral resection of bladder tumor (TURBT) in the treatment of recurrent bleeding in elderly patients with bladder cancer. Methods: From May 2003 to May 2013, 62 patients with advanced bladder cancer with recurrent bleeding were treated with TURBT. Results: All the 62 patients completed the operation successfully without any intraoperative blood transfusion. The patients were given intravesical instillation of chemotherapy with mitomycin 40 mg + 0.9% saline 40 ml after operation. The patients were followed up by telephone. The follow-up time ranged from 6 to 60 months (average 32 months). Both of them achieved good hemostatic effect, and their quality of life improved significantly. The 5-year survival rate was 79.0%. Conclusion: TURBT treatment of advanced bladder cancer with recurrent bleeding hemostasis effect of up to 100%, high safety factor, combined with mitomycin chemotherapy after surgery to achieve the purpose of treatment and improve quality of life.