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目的：探讨吸氧对慢性阻塞性肺病患者运动肺功能的影响。方法：１５例慢性阻塞性肺病患者于吸氧前后作递增型症状限制性运动（１０Ｗ／ｍｉｎ）和心输出量检查。运动中连续测量运动负荷、分时通气量、呼吸频率、潮气量及二氧化碳产生量。根据吸氧前后静息时分时通气量（·ＶＥ）和分时心输出量（ＣＯ）的变化，将１５例分为·ＶＥ减少组和·ＶＥ不减少组，ＣＯ减少组和ＣＯ不减少组。结果：吸氧明显增加·ＶＥｍａｘ、Ｗｍａｘ和ＳａＯ２ｍａｘ；但减少相同运动负荷时的·ＶＥ和·ＶＣＯ２。吸氧后，·ＶＥ减少组·ＶＥｍａｘ增加程度显著大于·ＶＥ不减少组；在相同运动负荷时ＣＯ不减少组的·ＶＥ下降程度显著大于ＣＯ减少组。结论：吸氧前后静息·ＶＥ的变化能够反映吸氧后运动能力的改善程度。
Objective: To investigate the effect of oxygen inhalation on exercise pulmonary function in patients with chronic obstructive pulmonary disease. Methods: Fifteen patients with chronic obstructive pulmonary disease (COPD) underwent incremental symptom-limited exercise (10 W / min) and cardiac output before and after oxygen inhalation. Exercise continuous measurement of exercise load, time-sharing ventilation, respiratory rate, tidal volume and carbon dioxide production. Fifteen patients were divided into · VE reduction group · VE non-reduction group, CO reduction group and CO non-reduction group according to changes of resting ventilation time (· VE) and timesaving cardiac output (CO) before and after oxygen inhalation . Results: Oxygen uptake significantly increased · VEmax, Wmax and SaO2max; but · VE and · VCO2 decreased with the same exercise load. After oxygen inhalation, • VE decreased group • VEmax increased significantly more than • VE did not reduce the group; in the same exercise load CO does not reduce the · VE decreased significantly more than CO reduction group. CONCLUSIONS: The change of resting VE before and after oxygen inhalation can reflect the improvement of exercise capacity after oxygen inhalation.