论文部分内容阅读
心肌缺血时,其能量储备很快耗尽,导致心肌细胞功能和心肌收缩性能下降,如能设法增加心肌的能量储备,心肌耐受缺氧的能力必定提高。作者给二尖瓣换置术的病人术前输注大剂量胰岛素,测定阻断主动脉一定时间后心肌细胞内高能磷酸盐的含量,以证明预防性应用胰岛素确能增加心肌的三磷酸腺甙储备,从而增进了低温和冷停跳液保护心肌的效应。病人和方法:20例拟行二尖瓣置换术的病人随机分成两组。两组病人的年龄、体表面积、心功能等级、体外循环时间以及主动脉阻断时间均相近;两组病人使用的体外循环机器、预充液、麻醉方式以及心
Myocardial ischemia, its energy depletion will soon be depleted, leading to myocardial cell function and myocardial contractility decreased, as can try to increase myocardial energy reserve, myocardial hypoxia tolerance must increase. The author of mitral valve replacement patients preoperative infusion of large doses of insulin, determination of aortic artery block after a certain period of high-energy phosphate content, to prove that prophylactic use of insulin can indeed increase cardiac adenosine triphosphate Reserve, thereby enhancing the effect of hypothermia and cold stop-jumping on myocardial protection. Patients and Methods: Twenty patients scheduled for mitral valve replacement were randomized into two groups. The age, body surface area, cardiac function grade, cardiopulmonary function time, and aortic cross-clamping time were similar in both groups. Extracorporeal circulation machines, priming fluid, anesthesia and heart