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目的探讨乳腺小管癌的临床病理特征,诊断与鉴别诊断要点。方法通过对6例小管癌常规HE染色和免疫组化进行临床病理分析,结合文献对其临床表现,病理形态特点及鉴别诊断进行探讨。结果乳腺小管癌组织形态学特征为小管结构由单层上皮细胞构成,部分小管呈锐角状;免疫组化显示小管结构缺乏肌上皮,E-Cadherin阳性。病理诊断上需与硬化性腺病,微腺型腺病等进行鉴别。结论乳腺小管癌是一种高分化小管结构乳腺癌,其预后良好。
Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of breast cancer. Methods Six cases of small cell carcinoma of the conventional HE staining and immunohistochemistry for clinical and pathological analysis, combined with the literature on its clinical manifestations, pathological features and differential diagnosis were discussed. Results The histopathological features of the breast cancer showed that the tubule consisted of monolayer of epithelial cells and some of the tubules were acute-angled. Immunohistochemistry showed that the tubules lacked myoepithelial epithelium and had positive E-Cadherin. On the pathological diagnosis and sclerodendenosis, glandular adenosis and other identification. Conclusion Breast cancer is a well-differentiated ductal breast cancer with a good prognosis.