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目的：探讨颈内中心静脉导管原位置换的临床应用效果。方法将155例需要更换颈内静脉导管患者随机分为观察组和对照组，观察组77例，采用颈内静脉导管原位置换法；对照组78例，采用颈内静脉重新穿刺置管法。观察两组的一次穿刺成功率、出血量的差别。结果两组一次穿刺成功率差异无统计学意义(P>0.05)，观察组出血量比对照组少，两组差异有统计学意义(P0. 05), but the difference that a-mount of bleeding comparison was statistically significant (P<0. 05). Conclusion The internal jugular central venous catheter in situ replacement relieve the pain of puncture,and the procedure is safe and easy, at the same time the cost is economic and effec-tive.