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目的利用横断面基线调查,对深圳市1003名工厂劳务工白喉抗体水平进行调查研究,制定相应的免疫接种措施,加强对外来劳务工的管理。方法采用酶联免疫吸附试验检测白喉抗体。结果工厂外来劳务工来自全国28个省市自治区,年龄大部分在20~49岁之间,女性多于男性。1003名外来劳务工白喉抗体的阳性率为38.9%,其中男性为42.9%,女性为35.1%。劳务工5年内变换1种工作的白喉抗体阳性率为31.93%,变换7种或7种以上工作的劳务工抗体阳性率为21.43%。结论深圳市工厂劳务工白喉抗体水平偏低,随着年龄的增长,白喉抗体水平逐渐减退;劳务工变换工作越少,白喉抗体的阳性率越高。建议进一步提高和保持高水平的白百破混合制剂常规免疫接种率,防止白喉的暴发和流行,同时加强外来流动人口免疫接种的监测,并加强传染源的管理。
Objective To investigate the level of diphtheria antibody in 1003 laborers in Shenzhen using the cross-sectional baseline survey, and to develop appropriate immunization measures to strengthen the management of migrant workers. Methods The diphtheria antibodies were detected by enzyme-linked immunosorbent assay. Results The factory laborers came from 28 provinces and autonomous regions in China, most of whom were between the ages of 20 and 49, with more women than men. The positive rate of 1003 foreign workers in diphtheria was 38.9%, including 42.9% in males and 35.1% in females. The positive rate of diphtheria antibody that laborers changed one kind of work within 5 years was 31.93%, and the positive rate of labors antibody that transformed 7 kinds or more of work was 21.43%. Conclusions The level of diphtheria antibody in laborers in Shenzhen is low. With the increase of age, diphtheria antibody levels gradually diminish. The less labor labors change, the higher the positive rate of diphtheria antibodies. It is recommended to further improve and maintain the routine immunization rate of high-level penehyclidine mixed preparations, to prevent the outbreak and spread of diphtheria, and to strengthen the monitoring of immunization of migrants and to strengthen the management of sources of infection.