聚乳酸是一种脂肪族聚酯类可生物降解高分子材料,已成为生物降解医用材料领域中最受重视的材料之一。本文以D,L-乳酸(两种光学异构体)为原料,通过二步开环聚合法实验,探讨了乳酸合成D,L-丙交酯,以及丙交酯经重结晶提纯并充分干燥后,作为聚合单体进行聚合反应的反应历程中各种反应参数包括温度、反应时间、溶剂、催化剂种类等对丙交酯的产率和聚合产物的分子量的影响。 Polylactic acid, an aliphatic polyester biodegradable polymer, has become one of the most important materials in the field of biodegradable medical materials. In this paper, D, L-lactic acid (two optical isomers) as raw materials, through the two-step ring-opening polymerization experiments to explore lactic acid synthesis of D, L-lactide, and lactide after recrystallization purification and fully dried Various reaction parameters in the polymerization reaction as the polymerization monomer include temperature, reaction time, solvent, type of catalyst, etc. on the yield of lactide and the molecular weight of the polymerization product.