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目的:探讨ABO母儿血型不合的宫内诊断方法及中西医结合治疗的疗效。方法:对2010年12月—2013年11月在桐庐县妇幼保健院产检及住院分娩的血型为O型,其丈夫为非O型的1 982例孕妇进行IgG抗A(B)效价测定,≥1∶64为异常,≥1∶128时给予中西医结合治疗,追踪随访治疗效果及新生儿预后。结果:1IgG抗A(B)效价≥1∶64者631例,异常检出率31.8%。2对IgG抗A(B)效价≥1∶128的344例孕妇,采取中西医结合治疗的有281例,治疗率81.7%;其中有效235例,有效率83.6%。3分娩前母体血清IgG抗体效价与新生儿ABO溶血发生率相关。结论:定期检测孕妇IgG抗A(B)效价,可以宫内诊断ABO母儿血型不合,中西医结合治疗疗效显著。
Objective: To investigate the method of intrauterine diagnosis of ABO maternal and child blood group incompatibility and the curative effect of integrated traditional Chinese and western medicine. Methods: The anti-A (B) titer of 982 pregnant women whose husband was non-O-type was tested for type of O at childbirth and childbirth in Tonglu County from December 2010 to November 2013, ≥ 1:64 for the exception, ≥ 1: 128 when combined treatment of traditional Chinese and Western medicine, follow-up treatment and follow-up prognosis of newborns. Results: 1 IgG anti-A (B) titer ≥ 1:64 were 631 cases, the abnormal detection rate of 31.8%. Two pairs of 344 anti-A (B) titers ≥ 1: 128 344 pregnant women, taking Integrative Medicine in 281 cases, the treatment rate was 81.7%; of which 235 cases were effective, the effective rate was 83.6%. 3 The maternal serum IgG antibody titer before delivery is related to the neonatal ABO hemolysis incidence. Conclusion: The detection of IgG anti-A (B) titers in pregnant women on a regular basis can be used to diagnose the abnormal blood type of ABO maternal in the womb, and the curative effect of integrative medicine is obvious.