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[目的]探讨食管癌术后患者恶性狭窄发生的危险因素。[方法]回顾性分析198例在我院施行食管癌切除并行食管重建手术患者的资料。对性别、年龄、高血压史、病灶部位、术前白蛋白、术前血红蛋白、手术时间、病灶最深浸润深度、手术医生职称、病理类型、输血、淋巴结转移、淋巴结数目、淋巴结转移度、病理分期、手术径路、术后白蛋白、术后血红蛋白、吻合口瘘、切口感染情况与食管癌术后恶性狭窄的关系行单因素及多因素Logistic回归分析。[结果]术后出现恶性狭窄13例(6.6%)。多因素分析显示淋巴结转移度是狭窄发生的独立危险因素。[结论]淋巴结转移度≥0.5的食管癌患者术后易发生恶性狭窄。
[Objective] To explore the risk factors of malignant stenosis in postoperative esophageal cancer patients. [Methods] A retrospective analysis of 198 cases of esophageal resection in our hospital in patients with esophageal reconstruction of the data. Preoperative albumin, preoperative hemoglobin, operation time, the deepest infiltration depth of the lesion, the title of the surgeon, pathological type, blood transfusion, lymph node metastasis, lymph node number, lymph node metastasis, pathological stage , Surgical approach, postoperative albumin, postoperative hemoglobin, anastomotic fistula, incision infection and postoperative malignant esophageal stricture were analyzed by single factor and multivariate logistic regression analysis. [Results] Malignant stenosis occurred in 13 cases (6.6%). Multivariate analysis showed that lymph node metastasis was an independent risk factor for stenosis. [Conclusions] Malignant stenosis is easy to occur in patients with esophageal cancer with lymph node metastasis≥0.5.