散手运动员大运动量训练期安静时内皮素、降钙素基因相关肽和心钠素水平变化的探讨(英文)

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采用放射免疫方法测定了 9名武术散手运动员大运动量训练期安静时内皮素(endothelin ,ET)、降钙素基因相关肽 (calcitoningenerelatedpeptide ,CGRP)和心钠素 (atrialnatyiureticpeptide ,ANP)等心血管激素 .随着大运动量训练的深入 ,散手运动员血浆ET水平呈逐渐升高趋势 ,直至后两次取样点时出现显著差异 .剧烈运动时 ,血浆儿茶酚胺及血管紧张素浓度增加 ,刺激ET分泌增加 .另外 ,骨骼肌和心肌缺血、缺氧或损伤 ,也可导致ET的分泌增加 .训练初期散手运动员血浆CGRP水平逐渐下降 ,但无显著差异 ,随着训练时间的延长该激素水平下降明显 ,表明与短时间极限运动的作用不同 ,长期训练可使机体CGRP分泌减少 .ET/CGRP比值的变化随着训练时间的推移 ,呈逐渐上升趋势 .ANP水平在训练初期显著提高 ,之后的训练中始终高于训练前 ,到最后测试点时与其前两个点比较也有显著差异 ,说明比赛前大强度训练对散手运动员心脏激素的作用很大 .ET与CGRP之间的变化具有明显的负相关 ,CGRP与ANP之间具有非常显著的负相关 ,ET与ANP之间有非常显著的正相关 .ET、CGRP和ANP水平变化与血液浓缩无关 . Radioimmunoassay was used to measure the plasma levels of endothelin (ET), calcitonin gene related peptide (CGRP) and atrial natriuretic peptide (ANP) in 9 Wushu Sanshou athletes during the high exercise training period. .With the deepening of the training of large amount of exercise, the level of plasma ET in Sanshou athletes increased gradually until the last two sampling points when there was a significant difference.During strenuous exercise, plasma catecholamines and angiotensin concentrations increased to stimulate ET secretion. In addition, skeletal muscle and myocardial ischemia, hypoxia or injury, can also lead to increased secretion of ET. Sanshou training athletes plasma CGRP levels gradually decreased, but no significant difference, with training time prolonging the hormone levels decreased significantly, It shows that, unlike the short-term extreme exercise, long-term training can reduce the body’s CGRP secretion.ET / CGRP ratio changes with the training time is gradually increasing.ANP levels increased significantly in training early after training always Higher than before training, to the last test point compared with the first two points are also significant differences, indicating that the game Pre-intense training played a significant role in the process of heart-hormones in Sanshou players. There was a significant negative correlation between ET and CGRP, negative correlation between CGRP and ANP, and significant positive correlation between ET and ANP Related changes in ET, CGRP and ANP levels have nothing to do with hemoconcentration.
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