氰化物在体内代谢大部成为硫代氰酸。后者曾广泛用于治疗高血压,但由于其毒性,包括致甲状腺肿,而被放弃。虽然如此,对于氰化物的慢性毒性还没有类似的报导。作者对于3个电镀工厂36名接触氰化物的工人和20名对照进行了临床和实验室检查,发现长期(工龄5～15年)接触氰化物产生甲状腺功能异常。电镀池所用的溶液含有3%氰化铜, Most cyanide cyanuric acid metabolism in the body. The latter has been widely used to treat high blood pressure, but was abandoned because of its toxicity, including causing goitre. Nevertheless, there is no similar report on the chronic toxicity of cyanide. The authors conducted clinical and laboratory tests on 36 cyanide-exposed workers and 20 controls at three electroplating plants and found that long-term exposure to cyanide (5-15 years of age) produced thyroid dysfunction. The solution used in the plating bath contains 3% copper cyanide,