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5. Predefined GPGRAFY-Epitope-Specific Monoclonal Antibodies with Different Activities for Recognizing

Predefined GPGRAFY-Epitope-Specific Monoclonal Antibodies with Different Activities for Recognizing

来源 :Tsinghua Science and Technology | 被引量 : 13次 | 上传用户：wangcong1001

【摘 要】

：

A seven-amino acid epitope GPGRAFY at the tip of the V3 loop in HIV-1 gp120 is the principal neutralizing epitope, and a subset of anti-V3 antibodies specific for this epitope shows a broad range of n

【作 者】

：

蓝灿辉 田海军 陈应华 

【机 构】

：

Laboratory of Molecular Immunology,Protein Science Laboratory of the Ministry of Education

【出 处】

：

Tsinghua Science and Technology

【发表日期】

：

2004年04期

【关键词】

：

human immunodeficiency virus type 1 gp120 (HIV-1 gp120) GPGRAFY-epitope monoclon 

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论文部分内容阅读

A seven-amino acid epitope GPGRAFY at the tip of the V3 loop in HIV-1 gp120 is the principal neutralizing epitope, and a subset of anti-V3 antibodies specific for this epitope shows a broad range of neu-tralizing activity. GPGRAFY-epitope-specific neut

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