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目的:观察尼群地平与倍他乐可治疗原发性高血压的疗效,尼不良反应及对患者生化代谢的影响。方法:85例原发性高血压患者,每日服尼群地平和倍他乐可片,观察血压、不良反应及生化指标。结果:显效73例(85%),有效11例(13%),总有效率84例(98%)。降压幅度:治疗前收缩压为22.6kpa±1.5kpa,舒张压为13.7kpa±0.68kpa,治疗后收缩压为17kpa±1.34kpa,舒张压为11.3kpa±0.8kpa,不良反应:头痛、头晕、皮肤潮红、乏力发生率7例(8%)。治疗前后空腹血糖、血脂、肾功能无显著变化(p﹥0.05)。结论:疗效确切,不良反应少。
OBJECTIVE: To observe the efficacy of nitrendipine and betatrexol in the treatment of essential hypertension, the adverse reactions of nystagmus and the effects on the biochemical metabolism in patients. Methods: Eighty-five patients with essential hypertension were treated with nitrendipine and betametazole daily. Blood pressure, adverse reactions and biochemical parameters were observed. Results: 73 cases were markedly effective (85%), 11 cases were effective (13%), and the total effective rate was 84 cases (98%). Pressure reduction range: systolic blood pressure before treatment 22.6kpa ± 1.5kpa, diastolic pressure of 13.7kpa ± 0.68kpa, systolic blood pressure after treatment was 17kpa ± 1.34kpa, diastolic blood pressure 11.3kpa ± 0.8kpa, adverse reactions: headache, dizziness, Skin flushing, fatigue in 7 cases (8%). Before and after treatment, fasting blood glucose, blood lipids and renal function had no significant changes (p> 0.05). Conclusion: The curative effect is definite, the adverse reactions are few.