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目的评价2010-2013年癫痫防治管理项目在宁夏实施的效果,为进一步加强癫痫防治提供科学依据。方法按照国家癫痫防治管理项目的要求,对筛查确诊的4 183例惊厥性癫痫患者进行规范化苯巴比妥药物治疗,观察治疗期间患者癫痫的月发作次数、发作情况、药物不良反应及患者退组情况,并对其效果进行评价。结果 2010-2013年,共筛查确诊4 330例惊厥性癫痫患者,治疗期间有147(3.39%)例患者因依从性差等原因退出治疗。入组管理的4 183例患者中,82.95%的患者苯巴比妥药物服用剂量为60~150 mg/d;治疗满4年的患者治疗显效率为80.25%;随着治疗周期的延长,患者月发作次数明显减少;患者出现不良反应大多发生在入组治疗前3个月,随着治疗时间的延长,不良反应发生率逐步下降。结论癫痫防治管理项目在宁夏实施的成效显著。
Objective To evaluate the effect of epilepsy prevention and control project implemented in Ningxia from 2010 to 2013 and provide scientific evidence for further strengthening the prevention and treatment of epilepsy. Methods According to the requirements of the National Epilepsy Prevention and Control Project, 4 183 cases of convulsive epilepsy diagnosed by screening were treated with phenobarbital, and the number of seizures, seizures, adverse drug reactions and patients’ withdrawal of epilepsy were observed during the treatment Group situation, and evaluate its effectiveness. Results A total of 4 330 convulsive epilepsy patients were screened during 2010-2013. 147 (3.39%) patients were withdrawn from treatment due to poor compliance. Of the 4,183 patients enrolled in the study, 82.95% had a phenobarbital dose of 60-150 mg / day; 80.25% of patients treated for 4 years had a marked response rate of 80.25%; with prolonged treatment, patients The number of monthly seizures decreased significantly; Most patients had adverse reactions occurred in the first 3 months before treatment, with the extension of treatment time, the incidence of adverse reactions decreased gradually. Conclusion Epilepsy management project implemented in Ningxia has achieved remarkable results.