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目的 :探讨女性尿道原发性恶性黑色素瘤的临床特征及治疗手段。方法 :对 3例女性原发性尿道恶性黑色素瘤进行临床病理分析及随访观察。结果 :3例均以尿道外口包块就诊。 2例因术前诊断不清 ,仅局部切除 ,其中 1例术后半年死于肿瘤复发。 1例正在随访中 ;1例行全尿道切除 ,双侧腹股沟淋巴结清扫及永久性膀胱造瘘。结论 :女性尿道原发性恶性黑色素瘤恶性度高 ,临床易误诊 ,早期确诊的主要依据是病理学检查 ,及时规范手术是提高患者生存率的主要手段
Objective: To investigate the clinical features and treatment of primary malignant melanoma in female urethra. Methods: Three cases of primary urethral malignant melanoma were observed clinically and pathologically. Results: Three cases were treated with urethral mass. Two cases of unclear due to preoperative diagnosis, only partial resection, of which 1 died of tumor recurrence six months after surgery. One patient was under follow-up. One patient underwent total urethral resection, bilateral inguinal lymph node dissection and permanent cystostomy. Conclusions: The primary malignant melanoma of urethra is highly malignant and easily misdiagnosed in clinic. The main basis of early diagnosis is pathological examination, and the regular operation is the main means to improve the survival rate of patients