论文部分内容阅读
目的了解脑卒中患者的胰岛素抵抗和代谢异常。方法以空腹血糖和空腹胰岛素乘积的倒数作为胰岛素敏感性指数，对４３例脑卒中患者和２１例对照者进行研究，并分别检查血脂代谢情况。结果脑卒中组无论是否合并高血压均存在胰岛素抵抗、高胰岛素血症（Ｐ＜０．０１）。胰岛素敏感性与低密度脂蛋白浓度呈负相关（ｒ＝－０．３１，Ｐ＜０．０５），与高密度脂蛋白浓度呈正相关（ｒ＝０．４６，Ｐ＜０．０１）。结论脑卒中患者体内胰岛素抵抗、高胰岛素血症与血脂代谢存在密切相关性
Objective To understand the insulin resistance and metabolic abnormalities in stroke patients. Methods Using the reciprocal of product of fasting blood glucose and fasting insulin as insulin sensitivity index, 43 stroke patients and 21 control subjects were studied, and the lipid metabolism was examined respectively. Results There was insulin resistance and hyperinsulinemia in stroke group with or without hypertension (P <0.01). Insulin sensitivity was negatively correlated with low density lipoprotein (r = -0.31, P <0.05), and positively correlated with high density lipoprotein (r = 0.46, P <0.01). Conclusion There is a close relationship between insulin resistance, hyperinsulinemia and lipid metabolism in stroke patients