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用套式ＰＣＲ法对２５例人类免疫缺陷病毒Ｉ型（ＨＩＶ－Ｉ）感染者和１７例对照组血清作了ＨＣＶ－ＲＮＡ检测。ＨＣＶＲＮＡ阳性者９例，其中４例有输血或接受过血制品史，３例为静脉药瘾者（ＩＶＤＵＳ），另２例与ＨＩＶ阳性患者有ＩＶＤＵＳ和性接触史，对照组无１例阳性。有输血／血制品和ＩＶＤＵＳ危险因素的患者的ＨＣＶＲＮＡ检测的阳性率最高（８０％和５０％）。在ＨＩＶ伴ＨＣＶ感染的全部病例中，仅２例曾有ＡＳＴ和ＡＬＴ轻度升高。本研究表明，这两种病毒伴随感染率之高是与其相同的传播途径危险因素有关，而未发现此两种病毒间可能相互影响的证据。
HCV-RNA was detected in 25 serogroup HIV-I infected patients and 17 control subjects using nested PCR. There were 9 cases of HCVRNA positive, including 4 cases of transfusion or history of blood transfusions, 3 cases of intravenous drug addiction (IVDUS), 2 cases of IVDUS and history of sexual contact with HIV-positive patients, and none in the control group. Patients with blood transfusion / blood products and IVDUS risk factors had the highest HCV RNA detection rates (80% and 50%). In all cases of HIV with HCV infection, only 2 patients had mildly elevated AST and ALT. The present study shows that the high rates of concomitant infection with these two viruses are related to their risk factors for the same route of transmission, with no evidence of a possible interaction between the two viruses.