西布曲明曾经是明星减肥药,主要通过抑制食欲,减少能量摄入达到减肥的目的。但它的副作用很大,轻则口渴、心慌、失眠,重则产生神经损伤和精神性疾病,因此欧美、澳洲等国家和地区纷纷禁用此药。在2010年10月30日,当时的国家食品药品监督管理局(国家食品药品监督管理总局的前身)叫停西布曲明制剂和原料药的生产、销售和使用,撤销其批准 Sibutramine has been a star diet pills, mainly through the suppression of appetite, reduce energy intake to achieve the purpose of weight loss. However, its side effects are great, ranging from thirst, palpitation, insomnia, and severe neurological damage and mental illness, so Europe and the United States, Australia and other countries and regions have banned the drug. On October 30, 2010, the then State Food and Drug Administration (the predecessor of the State Food and Drug Administration) halted the production, sale and use of sibutramine preparations and APIs, withdrew its approval