肾舒冲剂为卫生部药品标准收载,采用水提醇沉工艺制备。本实验分别用壳聚糖、乙醇对其水提液作澄清处理,以处方中主药黄柏所含成分小檗碱为指标,进行含量比较,并以正交设计法优选壳聚糖的最佳澄清工艺。1　药品、试剂和仪器中药材购自上海市药材公司;小檗碱对照品购于中国药品 Shenshu granules are collected by the Ministry of Health and are prepared by water extraction and alcohol precipitation. In this experiment, the aqueous extracts of chitosan and ethanol were used for clarification treatment. The content of berberine contained in the prescription of the main drug Phellodendron was used as the index, and the content was compared. The optimum of chitosan was optimized by orthogonal design method. Clarification process. 1 Drugs, reagents and instruments were purchased from Shanghai Medicinal Company; berberine reference products were purchased from Chinese drugs