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成人ＡＮＬＬ初治患者６１例用ＨＡ方案和ＤＡ方案治疗的效果相似（包括ＣＲ率，中位缓解时间），而ＨＡ方案的心脏毒性及并发严重感染率均较ＤＡ方案少见和轻微（Ｐ＜０．０５）。成人ＡＮＬＬ１４０例用ＶＭＰ或ＶＤＰ方案治疗的效果相仿，而ＶＭＰ方案治疗骨髓抑制率及并发严重感染率较少见和轻微（Ｐ＜０．０５）。结果表明，ＨＡ或ＶＭＰ方案对白血病细胞均有明显的杀伤，可以分别替代ＤＡ和ＶＤＰ方案，具有实用价值；ＨＡ和ＨＡＴ方案疗效相似，在ＶＭＰ方案中加ＣＴＸ可能提高疗效。
The efficacy of HA regimen and DA regimen was similar in 61 patients with initial ANLL in adults (CR rate and median remission time), while the HA toxicity and concurrent serious infection rate in HA regimen were both less and less than those in DA regimen (P <0 .05). The effect of ANLL140 in patients with VMP or VDP regimen was similar to that of adult ANLL140 patients. However, the rate of myelosuppression and concurrent serious infection in VMP regimen were less common and mild (P <0.05). The results showed that the HA or VMP regimen showed obvious cytotoxicity on leukemic cells, which could replace the DA and VDP regimens, respectively. It was of practical value. The efficacy of HA and HAT regimens was similar. Adding CTX to VMP regimen might improve the efficacy.