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目的探讨慢性阻塞性肺疾病(COPD)治疗及预防。方法从1996年开始,选COPD终末期(Ⅳ级)患者100例,50例试用大环内酯类、抗过敏药、化痰药、联合抗胆碱药、β受体兴奋剂及综合治疗,50例对照,仅使用化痰药、联合抗胆碱药、β受体兴奋剂及综合治疗。结果经以上治疗,明显减少其住院次数,住院费用减低。使其生活质量明显提高,无明显耐药性增加等不良反应。结论包括大环内酯类抗生素的综合治疗方法对COPD终末期患者身活质量提高,减少住院次数,有明显作用,且无明显增加患者耐药菌产生。
Objective To investigate the treatment and prevention of chronic obstructive pulmonary disease (COPD). Methods From 1996, 100 patients with end-stage COPD (grade Ⅳ), 50 patients with macrolides, anti-allergy drugs, expectorant drugs, combined anticholinergic drugs and β-receptor agonists, and 50 patients , Only phlegm drugs, combined with anticholinergic drugs, β-receptor agonists and comprehensive treatment. The results of the above treatment, significantly reduce the number of hospitalizations, hospitalization costs reduced. So that their quality of life improved significantly, no significant increase in drug resistance and other adverse reactions. Conclusion The comprehensive treatment including macrolide antibiotics has a significant effect on improving the quality of life and reducing the frequency of hospitalization in patients with end-stage obstructive pulmonary disease, and no significant increase in drug-resistant bacteria.