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目的:评价CT导引下125-I粒子置入治疗腹膜后转移瘤的疗效。方法:32例患者,男性21例,女性11例,年龄29～82岁,中位年龄57岁。其中肝癌术后转移11例,胰腺癌术后转移7例,胃癌术后转移8例,结直肠癌术后转移6例。按WHO疼痛程度分级标准,I级5例,II级16例,III级11例;药物止痛效果欠佳。在CT导引下行125-I粒子置入治疗。结果:32例疼痛患者中,1周有效率81.13%。1月有效率90.63%。3月有效率96.88%。6月有效率93.75%。32例腹膜后肿块患者中,1月有效率81.25%。3月有效率87.50%。6月有效率93.75%。结论:CT导引下125-I粒子置入治疗腹膜后转移瘤是一种安全有效的微创治疗方法,对控制疼痛症状及抑制肿瘤生长均有良好疗效。
OBJECTIVE: To evaluate the efficacy of CT-guided 125-I particle implantation in the treatment of retroperitoneal metastases. Methods: 32 patients, 21 males and 11 females, aged 29 to 82 years, with a median age of 57 years. Among them, 11 cases were postoperative metastasis of liver cancer, 7 cases were postoperative metastasis of pancreatic cancer, 8 cases were postoperative metastasis of gastric cancer, 6 cases were postoperative metastasis of colorectal cancer. According to WHO grade of grading standards, I grade in 5 cases, II grade in 16 cases, III grade in 11 cases; poor analgesic effect. Guided by CT-guided 125-I particle placement. Results: Among the 32 patients with pain, the effective rate was 81.13% in one week. January efficiency of 90.63%. March efficiency of 96.88%. The effective rate in June was 93.75%. In 32 patients with retroperitoneal mass, the effective rate was 81.25% in January. March efficiency of 87.50%. The effective rate in June was 93.75%. CONCLUSION: CT guided 125-I particles implantation in the treatment of retroperitoneal metastases is a safe and effective minimally invasive treatment, which has good curative effect on the control of pain symptoms and tumor growth inhibition.