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近年报道，血管壁存在肾素·血管紧张素系统（reinansiotensinsystem，RAS）和激肽系统，主要在内皮细胞。血管紧张素转换酶（angiotensinconvertingenzyme，ACE）是一种二肽凌基肽酶，主要存在于血管内皮细胞表面，可转化血管紧张素Ⅰ为血管紧张素Ⅱ，失活缓激肽。ACE抑制剂Ca
In recent years, it has been reported that the renin-angiotensin system (RAS) and kinin system exist in the vascular wall, mainly in endothelial cells. Angiotensin converting enzyme (ACE) is a dipeptidyl peptidase, which is mainly found on the surface of vascular endothelial cells. It can transform angiotensin Ⅰ into angiotensin Ⅱ and inactivate bradykinin. ACE inhibitor Ca