论文部分内容阅读
目的结合我院16例临床资料,探讨能否打破常规,使用干扰素治疗乙型肝炎后肝硬化失代偿期患者并观察其疗效。方法对我院2003年1月至2009年6月尝试使用干扰素治疗的16例乙型肝炎后肝硬化失代偿期患者的病例选择、干扰素治疗的方法、不良反应及疗效进行分析。结果 16例中15例存活,6例HBV-DNA阴转,5例肝硬化失代偿症状消失,肝功能恢复正常,余病情明显好转。结论干扰素治疗部分乙型肝炎后肝硬化失代偿期患者有很好的疗效,乙型肝炎后肝硬化失代偿期并非是使用干扰素抗病毒治疗的绝对禁忌证。
Objective To analyze the clinical data of 16 cases in our hospital to explore whether we can break the routine and use interferon to treat patients with decompensated liver cirrhosis after hepatitis B and observe its curative effect. Methods From January 2003 to June 2009 in our hospital try interferon treatment of 16 cases of hepatitis B patients with decompensated liver cirrhosis, the choice of interferon therapy, adverse reactions and efficacy analysis. Results Of 16 cases, 15 cases survived, 6 cases of HBV-DNA were negative, 5 cases of decompensation of liver cirrhosis disappeared, liver function returned to normal, the remaining condition improved significantly. Conclusions Interferon is effective in treating some patients with decompensated hepatitis B after liver cirrhosis. The decompensation of cirrhosis after hepatitis B is not the absolute contraindication to using interferon antiviral therapy.