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98例乙重肝血清HBV-M表达分为:Ⅰ.活动感染型;Ⅱ.高复制型;Ⅲ,反应增强型;Ⅳ.HBV_2型。四型的肝性昏迷率、PTA均值及病死率比较差异均不显著,因此HBV-M表达类型与病情严重程度及预后无相关性。Ⅰ、Ⅱ、Ⅳ型中急重肝和亚重肝所占比例差异均显著,但Ⅲ型中两型所占比例差异不显著,表明Ⅲ型多表现为暴发性过程,Ⅰ型多为亚急性,Ⅱ、Ⅳ型仅出现于亚急性病人;急重肝与亚重肝发病机制不同;不同HBV-M表达类型病人宜采用不同的治疗方法。此外HBV_2型占5.1％,提示天津地区重型肝炎中亦有HBV_2感染。
The expression of HBV-M in 98 cases of B hepatitis B was divided into: active infection type Ⅱ high replication type Ⅲ reaction enhanced type Ⅳ HBV-2. Four types of hepatic coma, PTA mean and mortality were not significantly different, so the type of HBV-M and the severity of the disease and prognosis no correlation. There were significant differences in the proportions of acute and severe liver in type Ⅰ, Ⅱ and Ⅳ, but there was no significant difference in the proportion of type Ⅱ between type Ⅲ and type Ⅲ, which indicated that type Ⅲ mostly manifested as an outbreak and type Ⅰ mostly subacute , Ⅱ, Ⅳ type only appear in subacute patients; acute and severe liver pathogenesis of sub-liver different; different types of HBV-M patients should adopt different treatment methods. In addition, HBV_2 accounted for 5.1%, suggesting that severe hepatitis in Tianjin also have HBV_2 infection.