论文部分内容阅读
强直性脊柱炎是一种以骶髂关节炎性反应为主的慢性进行性疾病,其病因不明,早期诊断标志物和疾病活动进展指标存在缺陷。脂质组学能通过分析体内各种脂质代谢物的变化,比较其脂质代谢的特征,帮助分析强直性脊柱炎的病因、病变过程和辅助临床诊断,为强直性脊柱炎的研究提供新的思路和平台。文章就强直性脊柱炎的研究概况、脂质组学及其在强直性脊柱炎研究中的应用、脂质组学的研究方法做以概要性的介绍。
Ankylosing spondylitis is a chronic progressive disease predominantly involving the sacroiliac joint inflammatory response. Its etiology is unknown and early diagnostic markers and indicators of disease activity are deficient. Lipidomics can analyze the changes of various lipid metabolites in the body, compare the characteristics of lipid metabolism, help to analyze the etiology, pathological process and clinical diagnosis of ankylosing spondylitis, and provide new research for ankylosing spondylitis The idea and platform. In this paper, an overview of the research on ankylosing spondylitis, lipidomics and its application in the study of ankylosing spondylitis, lipidomics research methods to do an overview.