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目的探讨鼓膜穿刺负压吸引治疗急性分泌性中耳炎的临床疗效。方法将85例急性分泌性中耳炎患者随机分为两组。治疗组43例(48耳)采用鼓膜穿刺负压吸引治疗;对照组42例(47耳)采用鼓膜穿刺抽液治疗。另外两组均给予药物对症治疗,7 d为一个疗程。治疗1~2个疗程,分别比较两组患者在各个疗程结束后的疗效。所有患者均随访3个月以上,观察不良反应及并发症。结果第1个疗程结束时,治疗组与对照组的总有效率分别为81.2%、48.9%;第2个疗程结束时,治疗组与对照组的总有效率分别为93.8%和59.6%。两组疗效比较差异有统计学意义(χ2=4.129,3.959,均P<0.05)。治疗期间至术后3个月,两组患者均未出现明显不良反应及并发症。结论鼓膜穿刺负压治疗是治疗急性分泌性中耳炎的一种安全、可靠和有效的方法。
Objective To investigate the clinical efficacy of tympanic membrane aspiration in treatment of acute otitis media with effusion. Methods Eighty-five patients with acute secretory otitis media were randomly divided into two groups. In the treatment group, 43 cases (48 ears) were treated with tympanic membrane suction negative suction; in the control group, 42 cases (47 ears) were treated with tympanic membrane aspiration. The other two groups were given symptomatic treatment of drugs, 7 d for a course of treatment. Treatment of 1 to 2 courses of treatment were compared in both groups after the end of each course of treatment. All patients were followed up for more than 3 months to observe the adverse reactions and complications. Results At the end of the first course of treatment, the total effective rates of the treatment group and the control group were 81.2% and 48.9%, respectively. At the end of the second course of treatment, the total effective rates of the treatment group and the control group were 93.8% and 59.6%, respectively. The difference between the two groups was statistically significant (χ2 = 4.129,3.959, both P <0.05). During the treatment period to 3 months after operation, no obvious adverse reactions and complications occurred in both groups. Conclusion The tympanic membrane negative pressure therapy is a safe, reliable and effective method for the treatment of acute otitis media.