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目的： 探讨格雷夫斯病患者的补体C3、C4水平的变化。方法： 测定了40例初发格雷夫斯病患者及正常对照组的补体C3、C4水平及甲状腺激素水平，并进行对比分析。结果： 患者的C3为0．99±0．28g／L，C4为0．24±0．05g／L，均显著低于正常对照组的C3、C4水平[分别为1．17±0．25g／L和0．32±0．07g／L]（P ＜0．05,）。除患者的C3与C4有显著正相关（相关系数r ＝0．681，P ＜0．01）外，其余未发现有明显相关性。结论： 格雷夫斯病患者的C3、C4水平降低，可能与其参与免疫复合物的形成，致使被消耗有关。
Objective: To investigate the changes of complement C3 and C4 in Graves’ disease. Methods: The levels of complement C3 and C4 and thyroid hormone in 40 Graves’ disease patients and controls were measured and compared. Results: The patients’ C3 was .990.99 ± 0.28 ‰ g / L and C4 was 0.24 ± 0.05 ‰ g / L, which were significantly lower than the C3 and C4 levels of the normal control group [分1.17 ± 0.25 μg / L and 0.32 ± 0.07 μg / L] (P <0.05). In addition to the patient’s C3 and C4 had a significant positive correlation (correlation coefficient r = 0.681, P <0.01), the rest did not find significant correlation. Conclusion: Graves’ disease patients with decreased levels of C3, C4, may be related to its involvement in the formation of immune complexes, resulting in consumption.