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目的了解山东省烟台市慢性乙型病毒性肝炎患者的生命质量及其影响因素,为采取相应的干预措施提供参考依据。方法于2013年1月—2016年1月采用随机整群抽样方法对在烟台市传染病医院、烟台毓璜顶医院、烟台山医院和解放军第107医院就诊并接受治疗的230例慢性乙型病毒性肝炎患者进行问卷调查。结果烟台市慢性乙型病毒性肝炎患者生活质量总分为(58.64±11.23)分,属于较差范畴;其中,躯体疼痛和社会功能得分分别为(78.24±11.05)和(75.33±9.78)分,均属于良好范畴;总体健康、生理机能和情感职能得分分别为(65.44±12.63)、(69.39±11.82)和(63.75±12.42)分,均属于合格范畴;生理职能、精神健康和活力得分分别为(45.03±9.33)、(59.87±10.56)和(58.97±13.65)分,均属于较差范畴。多元线性逐步回归分析结果显示,年龄越大、人均年收入越低、病程越长及合并其他慢性疾病的烟台市慢性乙型病毒性肝炎患者,其生命质量越低。结论慢性乙型病毒性肝炎患者的总体生命质量较低,年龄、人均年收入、病程和是否合并其他慢性疾病是其生命质量的主要影响因素。
Objective To understand the quality of life and its influencing factors in patients with chronic hepatitis B in Yantai, Shandong Province, and to provide a reference for the corresponding interventions. Methods From January 2013 to January 2016, 230 patients with chronic hepatitis B who were treated and treated in Yantai Infectious Disease Hospital, Yantai Yuhuangding Hospital, Yantai Mountain Hospital and People’s Liberation Army No.107 Hospital were studied by random cluster sampling method. Patients were surveyed. Results The total quality of life of patients with chronic hepatitis B in Yantai was (58.64 ± 11.23) points, which belonged to the poorer category. The scores of somatic pain and social function were (78.24 ± 11.05) and (75.33 ± 9.78) (65.44 ± 12.63), (69.39 ± 11.82) and (63.75 ± 12.42) points, respectively, which belonged to the eligible category. The scores of physical function, mental health and vitality were (45.03 ± 9.33), (59.87 ± 10.56) and (58.97 ± 13.65) points, all belong to the worse category. The results of multivariate linear stepwise regression analysis showed that the quality of life of YCC patients with chronic hepatitis B were lower with the older age, the lower annual per capita income, the longer the course of disease and the combination of other chronic diseases. Conclusion The overall quality of life of patients with chronic hepatitis B is low, and their age, per capita annual income, duration of disease and other chronic diseases are the main factors affecting their quality of life.