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目的探讨开展G6PD检测的临床意义。方法对近2年内笔者所在医院出生的3809例新生儿进行细胞葡萄糖-6-磷酸脱氢酶检测。结果男性新生儿G6PD缺乏率为12.04%，女性新生儿为7.75%，比较有统计学意义(2=6.107，=0.026)，总缺乏率为10.11%；G6PD具体数值为57~2452 U/L，轻度缺乏242例(62.86%)，中度缺乏49例(12.73%)，明显缺乏63例(16.36%)，重度缺乏31例(8.05%)。结论开展红新生儿细胞葡萄糖-6-磷酸脱氢酶检测可帮助临床及早采取预防措施，控制诱因，预防溶血性贫血的发生，对G6PD缺乏患儿健康成长具有重要意义。“,”Objective Discussion on developing the clinical significance of detecting G6PD. Methods For cel glucose-6-phosphate dehydrogenase detected in 3809 cases of newborns in the recent 2 years in our hospital was born. Results Male neonatal G6PD deficiency rate is 12.04%, the female newborns was 7.75%, compared with statistical significance ( 2=6.107, =0.026), the total lack of rate was 10.11%; the G6PD value for the 57~2452 U/L concrete, 242 cases of mild deficiency (62.86%), moderate deficiency in 49 cases (12.73%), significant lack of 63 cases (16.36%), severe deficiency in 31 cases (8.05%). Conclusion The development of red cel glucose -6- phosphate dehydrogenase of neonatal clinical early detection can help to take preventive measures, control incentives, prevent the happening of hemolytic anemia, and it has important significance to the healthy growth of children with G6PD deficiency.