论文部分内容阅读
本实验对30例口腔扁平苔藓（OLP）患者使用氯喹（CQ）前后及30名健康人进行了红细胞免疫粘附功能（RCIA）和循环免疫复合物（CIC）检测，结果显示：未经治疗的OLP组红细胞C3b受体花环率和红细胞免疫复合物花环率降低，循环免疫复合物水平上升，与健康对照组比较有显著性差异；经CQ治疗后的OLP组红细胞C3b受体花环率和红细胞免疫复合物花环率较治疗前上升，经统计学处理有显著性差异，与健康对照组比较无显著性差异，循环免疫复合物水平较治疗前下降，与健康对照组比较无显著性差异。结果提示：改善红细胞免疫粘附功能可能为CQ治疗OLP的机理之一。
In this study, 30 patients with oral lichen planus (OLP) before and after the use of chloroquine (CQ) and 30 healthy people were detected by erythrocyte immune adhesion function (RCIA) and circulating immune complexes (CIC) test results showed that: untreated In the OLP group, the ratio of rosette of C3b receptor and the ratio of rosette of erythrocyte immune complex decreased and the level of circulating immune complex increased, which was significantly different from that of the healthy control group. The C3b receptor rosette rate of erythrocytes and erythrocyte immune The rosette rate of the complex increased compared with that before treatment, and there was significant difference after statistical treatment. There was no significant difference between the two groups. The level of circulating immunocomplex decreased compared with that before treatment. There was no significant difference compared with healthy control group. The results suggest that improving the immune function of erythrocyte may be one of the mechanisms of OLP in treating CQ.