慢性胰腺炎胰管狭窄患者内镜下放置支架的预后

来源 :世界核心医学期刊文摘(胃肠病学分册) | 被引量 : 0次 | 上传用户:hongmusong
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Goals: To assess outcomes following 6 months of endoscopic stenting for dominant pancreatic duct strictures in painful chronic pancreatitis. Background: Pancreatic stent placement may improve pain in chronic pancreatitis. Long-term outcomes after a 6-month period of stenting are unknown. Study: We identified all patients with chronic pancreatitis who underwent stenting of a dominant pancreatic duct stricture at one hospital. Stents were left in place for 6 months. Changes in weight, hospital visits, and narcotic use were analyzed. Results: Mean follow-up for the 15 subjects was 36 months; 87%improved following stent placement, and 11 (73%) completed 6 months of stent therapy. Hospital visits per subject decreased from 3.6 in the year prior to stent placement to 0.1 in the year after stent removal (P < 0.01). Oral narcotic use decreased from 33 mg MSO4/day in th e month prior to stenting to 2 mg MSO4/day in the 12 months after stent removal (P = 0.01). Mean weight change was -5 kg in the year prior to stenting and +3. 2 kg in the year after stent insertion (P < 0.01); 36%required endoscopic reint ervention during the follow-up period. Conclusions: Six months of stenting resu lted in sustained clinical improvement in most patients with chronic pancreatiti s and a dominant pancreatic duct stricture. Stenting was associated with subsequ ent weight gain, fewer hospital visits, and less narcotic use. Goals: To seek induction following 6-month endoscopic stenting for dominant pancreatic duct strictures in painful chronic pancreatitis. Background: Pancreatic stent placement may improve pain in chronic pancreatitis. Long-term outcomes after a 6-month period of stenting are unknown. Study: We identified all patients with chronic pancreatitis who underwent stenting of a dominant pancreatic duct stricture at one hospital. Stents were left in place for 6 months. Changes in weight, hospital visits, and narcotic use were analyzed. Results: Mean follow-up for the Eighty percent of improved stent placement, and 11 (73%) completed 6 months of stent therapy. Hospital visits per subject decreased from 3.6 in the year prior to stent placement to 0.1 in the year after stent removal (P <0.01). Oral narcotic use decreased from 33 mg MSO4 / day in th month with month prior to stenting to 2 mg MSO4 / day in the 12 months after stent removal (P = 0.01). Mean weight change was -5 kg ​​in th e year prior to stenting and +3. 2 kg in the year after stent insertion (P <0.01); 36% required endoscopic reint ervention during the follow-up period. Conclusions: Six months of stenting resu lted in sustained clinical improvement in most Patients with chronic pancreatiti s and a dominant pancreatic duct stricture. Stenting was associated with subsequen weight gain, fewer hospital visits, and less narcotic use.
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