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目的:探讨胃/十二指肠血吸虫病的临床及病理特点;分析血吸虫病与胃/十二指肠癌的关系.方法:对41例胃/十二指肠血吸虫病患者的临床资料进行回顾性研究,对全部病例的组织学切片重新进行镜下观察和分析.结果:胃/十二指肠血吸虫病胃镜活检漏诊率相当高(89.5%).患者大多数因合并胃/十二指肠癌或溃疡病来就诊.呕血、黑便是其常见症状.血吸虫虫卵沉积可直接导致黏膜糜烂或溃疡,并且使溃疡癌变率增加.本病也与慢性萎缩性胃炎相关.结论:血吸虫病可通过引起溃疡或慢性萎缩性胃炎两种途径使胃/十二指肠黏膜发生癌变的机会增加,二者具备一定的因果关系.但同时,在部分病例,血吸虫病与胃癌为偶然并存关系.
Objective: To investigate the clinical and pathological features of gastric / duodenal schistosomiasis and to analyze the relationship between schistosomiasis and gastric / duodenal cancer.Methods: The clinical data of 41 patients with schistosomiasis of stomach / duodenum were reviewed The results of microscopic observation and analysis of histological sections of all cases were retrospectively analyzed.Results: The missed diagnosis rate of gastric / duodenal schistosomiasis gastroscopy biopsy was very high (89.5%). Most of the patients were complicated by stomach / duodenum Cancer or ulcer disease, hematemesis, melena is its common symptoms Schistosoma eggs deposition can directly lead to mucosal erosion or ulcer, and make the ulcer cancer rate increased.The disease is also associated with chronic atrophic gastritis.Conclusion: Schistosomiasis can be By causing ulcer or chronic atrophic gastritis two ways to gastric / duodenal mucosa carcinogenesis increased chance of both have a certain causal relationship.But at the same time, in some cases, schistosomiasis and gastric cancer co-exist casually.