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激素避孕对平衡和听力的影响已有一些初步报告,但至今尚无内分泌紊乱时长期激素治疗对位听系统影响的报道。Janczewski等(1976)首先报导了30例口服避孕药对内耳功能的影响,以临床和眼震图作评价,认为前庭为血管病变。Siegler(1977)曾描述停用激素避孕药后眩晕消失。Hashem(1977)报导20例用避孕药时间不一的病人,作旋转和冷热试验表明治疗期间对平衡有影响。Kley等(1978)一组20～30岁可逆性突发聋病人,数月间发作3～4次,停用避孕药后发作停止。Okulicz(1978)报导4例长期避孕药治疗后出现单侧或双侧可逆性耳聋,年龄19～40岁,疗程8月至10年。一例听力图坡度平坦,其余斜向高音。3例听力逐渐下降主要为血管堵塞,1例突然下降推测为迷路动脉栓塞。
Hormonal contraception has had some initial reports on the effects of balance and hearing, but until now there has been no report of the effects of long-term hormonal therapy on the hearing system in the absence of endocrine disorders. Janczewski et al. (1976) first reported the effects of 30 oral contraceptives on the inner ear function. Clinical and nystagmography were used to evaluate the vestibular function as a vascular lesion. Siegler (1977) described dizziness disappearing after steroid contraceptive use. Hashem (1977) reported 20 patients with contraceptives at varying times of rotation and hot and cold tests that showed an effect on the balance during treatment. Kley et al (1978) a group of 20-30-year-old reversible deafness patients, episodes of three to four times a few months, stop using the pill after the onset of seizures. Okulicz (1978) reported 4 cases of long-term contraceptives after unilateral or bilateral reversible deafness, aged 19 to 40 years of treatment from August to 10 years. A case of audiogram flat slope, the other oblique treble. Three cases of hearing loss decreased mainly vascular occlusion, a sudden decline was presumed to be lost arterial embolism.