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目的了解开封市妇女宫颈癌发病率,早期发现和及时治疗宫颈癌和癌前病变,降低宫颈癌的发病率和病死率。方法采用宫颈脱落细胞DNA定量分析系统,对参加开封市两癌普查的12 278例妇女中自愿检测宫颈DNA倍体细胞的2344例进行DNA倍体异常细胞分析。结果 2344例被检测者中DNA倍体异常并且在阴道镜下活检,经病理检查确诊为宫颈鳞癌者1例,确诊为子宫内膜腺癌1例,确诊为原位癌者3例,宫颈上皮内瘤变33例,占2.69‰。结论开封市妇女宫颈癌发病率为16.28/10万,采用宫颈脱落细胞DNA定量分析系统筛查宫颈癌,敏感性好,降低了宫颈癌的误诊率和漏诊率。
Objective To understand the incidence of cervical cancer in Kaifeng women, early detection and timely treatment of cervical cancer and precancerous lesions, reduce the incidence of cervical cancer and mortality. Methods Using DNA quantitative analysis system of cervical exfoliated cells, 2344 cases of cervical DNA ploidy cells were randomly selected from 12 278 women who participated in the screening of two cancers in Kaifeng for DNA ploidy abnormal cell analysis. Results 2344 cases were detected DNA ploidy abnormalities and biopsy in colposcopy, confirmed by pathological examination of cervical squamous cell carcinoma in 1 case, diagnosed as endometrial adenocarcinoma in 1 case, diagnosed with carcinoma in situ in 3 cases, cervical 33 cases of intraepithelial neoplasia, accounting for 2.69 ‰. Conclusions The incidence rate of cervical cancer in Kaifeng City is 16.28 / 100000. The screening of cervical cancer cells by DNA quantitative analysis system of cervical exfoliated cells has good sensitivity and reduces the misdiagnosis rate and misdiagnosis rate of cervical cancer.