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目的通过对某企业职业人群高尿酸血症患病率的调查,探讨高尿酸血症与心血管病危险因素的相关性,为职业人群健康管理提供理论依据。方法采用流行病学横断面研究方法对北京市、河北省唐山市、张家口市某企业18岁~60岁员工身体健康状况和生活方式进行了随机、分层、整群抽样问卷调查和体格检查。结果某企业员工高尿酸血症患病率为22.7%。收缩压、舒张压、低密度脂蛋白、BMI平均值和吸烟、饮酒的发生率在血尿酸正常组和高尿酸血症组间差异有统计学意义(P<0.05)。多因素Logistic回归结果显示性别、年龄、不锻炼、低密度脂蛋白胆固醇与高尿酸血症呈正相关(P<0.05),教育程度、高密度脂蛋白胆固醇与高尿酸血症呈负相关(P<0.05)。结论某企业职业人群高尿酸血症比例较高,高尿酸血症与心血管病危险因素有关,对高尿酸血症职业人群进行健康管理具有重要的公共卫生意义。
Objective To investigate the prevalence of hyperuricemia among occupational groups in an enterprise and to explore the correlation between hyperuricemia and risk factors of cardiovascular diseases so as to provide a theoretical basis for the health management of occupational groups. Methods By means of epidemiological cross-sectional study, randomized, stratified and cluster sampling questionnaires and physical examinations were conducted on the health status and life style of employees between the ages of 18 and 60 in an enterprise in Beijing, Tangshan City, Hebei Province and Zhangjiakou City. Results The prevalence of hyperuricemia in a company was 22.7%. Systolic blood pressure, diastolic blood pressure, low density lipoprotein, average BMI and the incidence of smoking and drinking were significantly different between the normal group and the hyperuricemia group (P <0.05). Multivariate logistic regression analysis showed that sex, age, not exercise, LDL cholesterol and hyperuricemia were positively correlated (P <0.05), education level, HDL cholesterol and hyperuricemia were negatively correlated (P < 0.05). Conclusion The proportion of hyperuricemia among occupational groups in a certain enterprise is high. Hyperuricemia is associated with the risk factors of cardiovascular diseases. It is of important public health significance to the health management of occupational hyperuricemia patients.