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目的探讨利用蓝光间断照射和持续照射对早产儿黄疸的治疗效果。方法 87例早产儿黄疸患儿,随机分为间断照射组(43例)和持续照射组(44例),间断照射组患儿接受间断蓝光照射治疗,持续照射组患儿接受持续蓝光照射治疗,比较两组患儿在治疗后血清总胆红素的变化、治疗效果和不良反应。结果治疗后,两组患儿的血清胆红素较治疗前显著下降(P<0.05),而粪胆红素较治疗前显著上升(P<0.05),但是两组间差异无统计学意义(P>0.05);间断照射组总有效率为97.67%;持续照射组总有效率为93.18%,差异无统计学意义(P>0.05);间断照射组不良反应发生率为4.65%;显著低于持续照射组的不良反应发生率18.18%(P<0.05)。结论两种蓝光照射方式都可以有效治疗新生儿黄疸,但是蓝光间断照射对新生儿产生的不良反应更少,可以在临床中推广使用。
Objective To explore the use of intermittent blue light irradiation and continuous irradiation on the treatment of jaundice in preterm infants. Methods 87 cases of jaundice in preterm infants were randomly divided into intermittent irradiation group (43 cases) and continuous irradiation group (44 cases). The intermittent irradiation group received intermittent blue light irradiation and the continuous irradiation group received continuous blue light irradiation. The changes of serum total bilirubin, therapeutic effect and adverse reaction in two groups were compared. Results After treatment, the level of serum bilirubin in both groups decreased significantly (P <0.05) and the level of bilirubin increased significantly (P <0.05), but there was no significant difference between the two groups (P> 0.05). The total effective rate in intermittent irradiation group was 97.67%. The total effective rate in continuous irradiation group was 93.18%, with no significant difference (P> 0.05). The incidence of adverse reactions in intermittent irradiation group was 4.65% The incidence of adverse reactions in continuous irradiation group was 18.18% (P <0.05). Conclusion Both methods of blue light irradiation can effectively treat neonatal jaundice, but intermittent irradiation with blue light has fewer adverse reactions to neonates and can be widely used in clinical practice.