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目的:探讨补锌治疗对婴幼儿迁延性肠炎的临床疗效。方法:将2007年3月至2009年2月在三亚市妇幼保健院儿科门诊诊断为迁延性肠炎(其诊断标准均符合《实用儿科学》第7版迁延性肠炎诊断标准)的婴幼儿80例随机分成治疗组及对照组各40例,两组患儿均严格按照腹泻病的治疗原则进行调整饮食、预防和纠正脱水、合理用药、加强护理、预防并发症等治疗。治疗组在常规治疗的基础上加用锌剂,用法及用量:<6月10 mg/d,>6月20 mg/d。结果:补锌治疗组总有效率为82.5%,常规治疗组总有效率为62.5%,两者相比差别有统计学意义(χ2=8.217,P<0.05)。结论迁延性肠炎在常规治疗的基础上佐以补锌治疗有较好的临床疗效。
Objective: To investigate the clinical effect of zinc supplementation on infantile childhood inflammatory bowel disease. Methods: From March 2007 to February 2009, 80 pediatric infants and young children diagnosed as prolonged enteritis in pediatric outpatient service in Sanya MCH hospital (diagnostic criteria were all consistent with the diagnostic criteria of the 7th edition of “Practical Pediatrics”) Randomly divided into treatment group and control group of 40 cases, two groups of children were strictly in accordance with the principles of diarrhea treatment to adjust diet, prevention and correction of dehydration, rational use of medication, and strengthen care and prevention of complications such as treatment. In the treatment group, zinc was added on the basis of routine treatment. Usage and dosage: <10 mg / d in June and> 20 mg / d in June. Results: The total effective rate was 82.5% in the zinc supplementation group and 62.5% in the conventional treatment group. There was a significant difference between the two groups (χ2 = 8.217, P <0.05). Conclusion Prolonged enteritis on the basis of conventional treatment with zinc supplementation have a better clinical efficacy.