【摘 要】
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Isonitrile group has been identified in many natural products.Due to the broad reactivity of N=C triple bond,these natural products have valuable pharmaceutical
【机 构】
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Department of Chemistry, North Carolina State University Raleigh, NC 27695, U.S.A.;State Key Laborat
论文部分内容阅读
Isonitrile group has been identified in many natural products.Due to the broad reactivity of N=C triple bond,these natural products have valuable pharmaceutical potentials.This review summarizes the current biosynthetic pathways and the corresponding enzymes that are responsible for isonitrile-containing natural product generation.Based on the strategies utilized,two fundamentally distinctive approaches are discussed.In addition,recent progress in elucidating isonitrile group formation mechanisms is also presented.
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