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甘露醇是一种高渗脱水剂,过去内科主要用于降颅压和防治急性肾功能衰竭。近年来,随着对其作用机理的不断认识,内科用途越来越广泛。现结合文献综述如下。一、治疗缺血性脑血管病有人用20%甘露醇250ml,日1～2次,连续5～7天,同时加低分子右旋糖酐500ml,日1次,连续14天治疗脑血栓形成48例。结果总有效率95.8%,明显高于对照组的47.1%(P<0.01)。还有人用低分子右旋糖酐500ml加复方丹参注射液10ml,20%甘露醇120ml静滴,日1次,共14天。结果总有效率86.7%,也明显优于对照组。王辉还用甘露醇治疗60例急性脑梗塞患者并与另外60例作对照。治疗组用20%甘露醇250ml
Mannitol is a hypertonic dehydration agent, used to reduce intracranial pressure and prevent acute renal failure. In recent years, with the continuous understanding of its mechanism of action, medical use is more and more widely used. Now combined with literature review is as follows. First, the treatment of ischemic cerebrovascular disease Some people with 20% mannitol 250ml, 1 to 2 times a day for 5 to 7 days, while adding low molecular weight dextran 500ml, day 1, for 14 consecutive days of cerebral thrombosis in 48 cases. The total effective rate was 95.8%, significantly higher than that of the control group (47.1%, P <0.01). There are people with low molecular weight dextran 500ml compound Danshen injection 10ml, 20% intravenous infusion of mannitol 120ml, day 1, a total of 14 days. The total effective rate of 86.7%, also significantly better than the control group. Wang Hui also used mannitol treatment of 60 patients with acute cerebral infarction and 60 cases with the control. The treatment group with 20% mannitol 250ml