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目的了解子宫肌瘤的患病风险与高血压、高血糖和高脂血症之间的关系。方法采用横断面研究方法,由体检医师于2008年对济南地区铁路系统6164名已婚在职女职工进行健康检查,妇科检查内容包括B超检查和妇科常规检查,并进行血压和空腹血糖、甘油三酯、胆固醇等指标的测定。同时以问卷方式收集研究对象的基本信息和疾病史等情况。按照研究对象是否患有子宫肌瘤分为两组,采用Logistic回归分析方法在控制其他影响因素条件下分析子宫肌瘤与高血压、高血糖、高脂血症之间的关联性。结果研究对象子宫肌瘤患病率为20.93%,平均年龄(40.07±8.20)岁;高血压、高血糖和高脂血症患病率分别为8.20%、3.09%和10.68%。高血压是子宫肌瘤的独立危险因素(OR=1.316,95%CI 1.064～1.627),舒张压每升高10mmHg子宫肌瘤患病风险增加17.1%(OR=1.171,95%CI 1.045～1.312)。结论高血压是子宫肌瘤独立的危险因素,并且子宫肌瘤患病风险随着舒张压水平的升高而增加。
Objective To understand the relationship between the prevalence of uterine fibroids and hypertension, hyperglycemia and hyperlipidemia. Methods The method of cross-sectional study was adopted. The physical examiners performed the health examination on 6164 married female employees in the railway system in Jinan in 2008. The gynecological examinations included B-ultrasound and routine gynecological examinations. Blood pressure and fasting blood glucose, triglyceride Ester, cholesterol and other indicators of determination. At the same time by questionnaire to collect the basic information of subjects and history of disease and so on. According to the study whether patients with uterine fibroids are divided into two groups, the use of Logistic regression analysis of other factors under the control of uterine fibroids and hypertension, hyperglycemia, hyperlipidemia association. Results The prevalence of uterine fibroids was 20.93% with an average age of 40.07 ± 8.20 years. The prevalence rates of hypertension, hyperglycemia and hyperlipidemia were 8.20%, 3.09% and 10.68%, respectively. Hypertension was an independent risk factor for uterine fibroids (OR = 1.316, 95% CI 1.064-1.627). The increased prevalence of uterine leiomyoma was 17.1% (OR = 1.171, 95% CI 1.045-1.312) . Conclusion Hypertension is an independent risk factor of uterine fibroids, and the risk of uterine fibroids increases with the increase of diastolic blood pressure.