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目的探讨血液灌流联合连续性血液滤过治疗急性中毒引起多器官功能障碍的治疗效果。方法对7例急性中毒合并多器官功能障碍的患者给予血液灌流(HP)联合连续性血液滤过(CRRT)治疗,观察治疗前后生化指标。结果 6例抢救成功,1例患者家属放弃治疗。患者治疗前后生化指标明显好转(P<0.05)。结论血液灌流(HP)联合连续性血液滤过(CRRT)治疗急性中毒合并多器官功能障碍效果显著。
Objective To investigate the therapeutic effect of hemoperfusion combined with continuous hemofiltration in the treatment of multiple organ dysfunction caused by acute poisoning. Methods Seven patients with acute poisoning and multiple organ dysfunction were given hemoperfusion (HP) and continuous hemofiltration (CRRT). The biochemical indexes before and after treatment were observed. Results 6 cases were successfully salvaged, and 1 patient’s family gave up treatment. Before and after treatment in patients with biochemical indicators improved significantly (P <0.05). Conclusion Hemoperfusion (HP) combined with continuous hemofiltration (CRRT) has significant therapeutic effect on acute poisoning combined with multiple organ dysfunction.