全反式维甲酸治疗骨髓增生异常综合征

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作者以国产全反式维甲酸(简称维甲酸)对20例骨髓增生异常综合征(MDS)进行治疗。患者男7例,女13例,年龄21~74岁。疗法:初服维甲酸片每次10毫克,每日3次,连服1~2周,如无明显肝损害并能耐受口干等副作用,可增加剂量到80~90毫克/日,分3~4次日服,连续服药至血象恢复正常,改为30毫克/日,维持用 The authors treat 20 cases of myelodysplastic syndrome (MDS) with domestic all-trans retinoic acid (retinoic acid for short). 7 patients were male and 13 females, aged 21 to 74 years. Therapy: First serving of retinoic acid tablets 10 mg each time, 3 times a day, and even for 1 to 2 weeks, such as no significant liver damage and can withstand dry mouth and other side effects, increase the dose to 80 to 90 mg / day, points 3 to 4 times a day, continuous medication until the blood returned to normal, to 30 mg / day, maintenance
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