The occurrence of interbeds in thick oil formations is one of the main reasons that cause the difference of remaining oil distribution. A quantitative method for predicting interbeds was proposed and the sedimentary origin and division criterion were demonstrated. The distribution of interbeds in different types of sedimentary sand bodies were predicted and analyzed by combining the theory of sedimentology and reservoir bed architectural-element analysis. The interbeds in a single well were recognized from high resolution well logs, and inter-well interbeds were predicted by using the methods of cyclothem correlation, physical properties truncation, and conditional simulation. Finally a 3-D model of interbed was built. Application to the Gudao Oilfield was successful.