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本文对近年来发展的中药指纹图谱技术及相应的化学计量学方法进行了讨论.在中药质量控制中,这些方法被广泛地应用于中药成品或半成品专属性和稳定性的确定.实质上,中药指纹图谱技术是一种探索中药复杂性的高通量整体性分析方法,所以,对其进行更深入的定性定量分析将对进一步全面控制中药质量和探明中药作用机理打下良好的化学基础.结合系统生物学与生物信息学方法,似有可能探明中药的作用机理,进而更全面地对中药质量进行控制.
This article discusses the development of traditional Chinese medicine fingerprinting techniques and corresponding methods of chemometrics. In the quality control of traditional Chinese medicines, these methods are widely used to determine the specificity and stability of finished or semi-finished products of traditional Chinese medicine. In essence, traditional Chinese medicine Fingerprinting technology is a high-throughput holistic analytical method to explore the complexity of Chinese medicine. Therefore, further qualitative and quantitative analysis of it will lay a good chemical foundation for further comprehensive control of the quality of Chinese medicine and the mechanism of proven Chinese medicine. System biology and bioinformatics methods may seem to be able to ascertain the mechanism of action of traditional Chinese medicines, and then more comprehensively control the quality of Chinese medicine.