临床上常习惯于将维生素B_6与异烟肼配合应用于结核病,以防止异烟肼的毒副作用。而当误服异烟肼中毒时,也常将维生素B_6作为特效解毒剂进行抢救。从异烟肼的作用机理及临床实践来看,异烟肼中毒时用维生素B_6进行抢救是较为合理的,也有过一些成功的报道,而对于正常使用异烟肼配伍维生素B_6,则有必要作进一步探讨。异烟肼的抗菌机理比较公认的说法,是异烟肼能与体内的醛、酮等物质结合形成睆,而醛类里边的吡 Clinical often accustomed to vitamin B_6 and isoniazid in combination with tuberculosis, to prevent the side effects of isoniazid. And when mistakenly isoniazid poisoning, vitamin B_6 is often used as a special antidote to rescue. Isoniazid from the mechanism of action and clinical practice point of view, isoniazid poisoning with vitamin B_6 rescue is more reasonable, there have been some successful reports, and for the normal use of isoniazid and vitamin B_6, it is necessary for Further Discussion. Isoniazid antibacterial mechanism is more generally accepted that Isoniazid can form albite with the body of aldehydes, ketones and other substances, and aldehydes inside the pyridine