氟康唑是一种口服抗真菌药物。本文叙述一种灵敏、准确、简便、费时少的GC法测定体液中的氟康唑。该法通过在碱性条件下,加入UK-47265(内标),用氯仿简单地抽提后,不需蒸发,即可用由涂非极性相的15m毛细管柱,连接一个选择性好、灵敏度高的氮选择性检测器的GC系统进行检测。每次分析时间<4min,相关系数为0.999,最低检出的血浆 Fluconazole is an oral antifungal drug. This article describes a sensitive, accurate, simple and time-consuming GC method for the determination of fluconazole in body fluids. The method by adding UK-47265 (internal standard) under alkaline conditions, simply extracted with chloroform, without evaporation, you can use a non-polar phase coated 15m capillary column connected to a good selectivity, sensitivity High Nitrogen Selectivity Detector GC system for testing. Each analysis time <4min, the correlation coefficient of 0.999, the lowest detected plasma