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目的观察并探讨用宫腔镜电切术联合米非司酮治疗黏膜下Ⅱ型子宫肌瘤的临床疗效及安全性。方法对2010年4月～2012年4月期间在我院妇产科住院治疗的98例黏膜下Ⅱ型子宫肌瘤患者的临床资料进行回顾性研究。我们应用随机数字表法将这98例患者分为对照组和治疗组,每组各有49人。两组患者均进行宫腔镜电切术治疗,其中治疗组患者在手术前加用米非司酮进行治疗。手术后,比较两组患者治疗的效果和发生不良反应的几率。结果治疗组患者治疗的有效率(95.92%)明显高于对照组患者(85.42%),且两组患者发生不良反应的几率无显著性差异(P>0.05)。结论用宫腔镜电切术联合米非司酮治疗黏膜下Ⅱ型子宫肌瘤疗效确切,不良反应少,安全可靠,值得在临床上推广使用。
Objective To observe and discuss the clinical efficacy and safety of hysteroscopic electrotomy combined with mifepristone in the treatment of submucosal type Ⅱ uterine fibroids. Methods The clinical data of 98 patients with submucosal type Ⅱ myoma of uterus treated in our hospital from April 2010 to April 2012 were retrospectively studied. We used random number table method these 98 patients were divided into control group and treatment group, each with 49 people. Two groups of patients were treated by hysteroscopic resection, in which the treatment group patients before treatment with mifepristone for treatment. After surgery, the effect of treatment and the incidence of adverse reactions in both groups were compared. Results The effective rate (95.92%) in the treatment group was significantly higher than that in the control group (85.42%). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Hysteroscopic electrotomy combined with mifepristone in the treatment of submucosal type Ⅱ uterine fibroids curative effect is accurate, less adverse reactions, safe and reliable, it is worth to promote the clinical use.